Jeff Faughender/USA Today Network via Reuters]
UPS (NYSE: UPS) confirms that one of its cargo aircraft was involved in a fatal accident shortly after departure from Louisville Muhammad Ali International Airport (SDF) on the evening of 3 November 2025.
According to reports from Reuters and the Associated Press, the aircraft — a Boeing 767 freighter — crashed less than two miles from the airport, erupting into flames after impact. Local authorities have confirmed multiple fatalities and several injuries, including individuals on the ground.
UPS immediately activated its Emergency Response Plan and is working closely with the National Transportation Safety Board (NTSB) and Federal Aviation Administration (FAA) to support ongoing investigations.
Carol Tomé, Chief Executive Officer of UPS, said:
“We are deeply saddened by this tragic event. Our hearts go out to the crew, their families, and all those affected. UPS is cooperating fully with authorities to understand what happened and to provide every possible support to those impacted.”
UPS representatives and crisis counselors are on-site, coordinating with local first responders and Louisville Metro emergency services. The company has also established a dedicated hotline for affected families and employees.
The Louisville Department of Public Safety, cited by AP, reported that fire and rescue teams worked overnight to contain the blaze and secure the crash site. Flight operations at Louisville’s UPS Worldport hub resumed in a limited capacity early Tuesday morning, with safety measures and operational adjustments in place.
UPS stated that no cause has yet been determined and cautioned against speculation pending the outcome of the NTSB’s formal investigation.
“Safety is the foundation of our operations,” said Jim Barber, President of UPS Airlines. “We are focused on supporting the investigation, our employees, and our community during this difficult time.”
UPS said it will provide regular factual updates in coordination with the NTSB and relevant authorities.

